it depends on ur skin concerns & the texture u prefer dear. there’s various types of essence & ampoule too including hydrating, calming , exfoliating etc. usually they r fine to use daily except for exfoliant essence/ampoule ( this has to depends on how well ur skin could tolerate the product, start slow & start with low % first , slowly build up ur skin tolerance) for exfoliant essence/toner I would recommend using at night, calming /soothing /hydrating essence/ampoule is safe to use both day & night 😇😇